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Dr. Jiyu Fang

AMPAC Director, Professor

MSE

Education

  • Ph.D. — Southeast University, 1992

Research

  • Biological Interfaces
  • Nano-scale Science and Engineering
  • Molecular Self-Assembly
  • Polymer Thin Films
  • Biotechnology
  • Soft Lithography
  • Scanning Probe Microscopy
  • Liquid Crystal Imaging Techniques
Dr. Fang's research focuses on the interdisciplinary area of physics, chemistry, materials and biology, with an emphasis on self-organized biological systems and self-assembled nanostructural materials. Technology development such as scanning probe microscopy, liquid crystal optical amplification, and soft lithography also plays a major role in his research activities. This area has rich opportunities for students both in fundamental science and practical technologies. There are four current projects in Dr. Fang's Group:
  1. Imaging order, defects and dynamics of biological interfaces with liquid crystals
  2. Stretching polymers and biopolymers in thin films with scanning probe microscope
  3. Nanomaterials based on self-assembly of biological building blocks such as lipids, peptides, DNA and Virus
  4. Protein crystal-directed assembly of 2-D and 3-D inorganic nanocrystals

Selected Publications

  1. X. Zhang, K. Tamhane, T. Bera, J. Y. Fang, “Transcription of pH-Sensitive Supramolecular Assemblies into Silica: From straight, Coiled, and Helical Tubes to Single and Double Fan-Like Bundles”. Journal of Materials Chemistry 2011. 21, 13973.
  2. J. Zou, J. Y. Fang, “Synthesis of Adhesive Polymer Dispersed Liquid Crystal Films”. Journal of Materials Chemistry 2011, 21, 9149.
  3. J. Zou, T. Bera, A. Davis, W. Liang, J. Y. Fang, “Director Configuration Transition of Polyelectrolyte Encapsulated Liquid-Crystal Droplets”. Journal of Physical Chemistry B 2011. 115, 8970.
  4. W. Liang, T. Bera, X. Zhang, A. J. Gesquiere, J. Y. Fang, “Boojum and Stripe Textures in Long Range Orientationally Ordered Monolayers on substrates”. Langmuir 2011, 27, 1051.
  5. X. Zhang, J. F. Fang, “Assembly of Vesicles into Fractal and Prong Patterns on Solid Substrates”. Soft Matter 2010, 6, 2139.
  6. K. Tamhane, X. Zhang, J. Zou, J. Y. Fang, “Assembly and Disassembly of Tubular Spherulites”. Soft Matter 2010, 6, 1224. (This paper is highlighted in Physics Week 2010, 06, 22).
  7. J. Zou, J. Y. Fang, “Director Configuration in Liquid-Crystals Droplets Encapsulated with Polyelectrolytes”. Langmuir 2010, 26, 7025.
  8. X. Zhang, M. Mathew, A. J. Gesquiere, J. Y. Fang, “Synthesis of Fluorescent Composite Tubes with pH-Controlled Shapes”. Journal of Materials Chemistry 2010, 20, 3716.
  9. Z. Zhang, J. Zou, K. Tamhane, F. Kobzeff, J. Y. Fang, “Self-Assembly of pH-Switchable Spiral Tubes: Supramolecular Springs”. Small 2010, 6, 217.
  10. Y. Zhao, L. An, J. Y. Fang, “Buckling Instability of Lipid Tubules with Multibilayer walls under Local Radial Indentation”. Physical Review E 2009. 80, 021911. (This paper is selected for publication in the August 24, 2009 issue of the Virtual Journal of Nanoscale Science & Technology and in the October 15, 2009 issue of the Virtual Journal of Biological Physics Research and highlighted in Vertical New 2009, 10, 18).
  11. Y. Zhao, Z. Ge, J. Y. Fang, “Elastic Modulus of Viral Nanotubes”. Physical Review E 2008, 78, 031914. (This paper is selected for publication in the September 29, 2008 issue of the Virtual Journal of Nanoscale Science & Technology and in the October 1, 2008 issue of the Virtual Journal of Biological Physics Research).
  12. Y. H. Lin, H. Ren, Y. H. Wu, S. T. Wu, Y. Zhao, J. Y. Fang, “Electrically Tunable Wettability of Liquid Crystal/Polymer Composite Films”. Optics Express 2008, 16, 17591. (It is selected for publication in the December 1, 2008 issue of the irtual Journal for Biomedical Optics).
  13. H. Wang, Z. Xie, W. Yang, J. Y. Fang, L. N. An, “Morphology Control in Vapor-Liquid- Solid Growth of SiC Nanowires”. Crystal Growth & Design 2008, 8, 3893.
  14. Y. Zhao, J. Y. Fang, “Zigzag Lipid Tubules”. Journal of Physical Chemistry B 2008, 112, 10964.
  15. Y. Zhao, K. Tamhane, X. Zhang, L. An, J. Y. Fang, “Radial Elasticity of Self-Assembled Lipid Tubules”. ACS Nano 2008, 2, 1466.
  16. Y. Zhao, J. Y. Fang, “Direct Printing of Lipid Tubules”. Langmuir 2008, 24, 5113.
  17. J. Y. Fang, “Ordered Arrays of Self-Assembled Lipid Tubules: Fabrication and Applications.” Journal of Materials Chemistry. 2007, 17, 3479. (Feature Article).
  18. Y. Zhao, L. An, J. Y. Fang, “Buckling of Self-Assembled Lipid Tubules in Shrinking Liquid Droplets”. Nano Letters 2007, 7, 1360.
  19. L. Guo, P. Chowdhury, J. Y. Fang, F. Gai, “Heterogeneous and Anomalous Diffusion of Molecules inside Lipid Tubules”. Journal of Physical Chemistry B 2007, 111, 14244.
  20. H. T. Wang, G. Q. Liu, W. Y. Yang, L. Lin, Z. P. Xie, J. Y. Fang, L. N. An, “Bicrystal AIN Zigzag Nanowires Induced by Crystal Lattice Mismatch”. Journal of Physical Chemistry C 2007, 111, 17169.
  21. Y. Zhao, J. Liu, Y. Sohn, J. Y. Fang, “Synthesis of Hybrid Lipid-Silica Cylinders with Nanoscale Helical Ripples”. Journal of Physical Chemistry C 2007, 111, 6418.
  22. Y. Zhao, N. Mahajan, J. Y. Fang, “Fabrication of Self-Assembled Cylindrical Lipid Tubules with Birefringent Core”. Small 2006, 2, 364.
  23. Y. Zhao, N. Mahajan, S. Long, Q. Wang, J. Y. Fang, “Stability and Deformation of Virus Nanoparticles under Applied Load with Atomic Force Microscope”. Micro and Nano Letters 2006, 1, 1.
  24. Y. Zhao, N. Mahajan, J. Y. Fang, “Bending and Radial Deformation of Self-Assembled Hollow Cylindrical Lipid Tubules”. Journal of Physical Chemistry B 2006, 110, 22060.
  25. N. Mahajan, Y. Zhao, T. B. Du, J. Y. Fang, “Nanoscale Ripples in Self-Assembled Lipid Tubules”. Langmuir 2006, 22, 1973.
  26. Y. Zhao, J. Y. Fang, “Alignment and Positioning of Lipid Tubules on Patterned Au Substrates under Flow and Confinement”. Langmuir 2006, 22, 1892.
  27. Y. H. Lin, H. W. Ren, Y. H. Wu, Y. Zhao, J. Y. Fang, S. T. Wu, “IPS-LCD Using A Glass Substrate and an Anisotropic Polymer Film”. Journal of Display Technology 2006, 2, 21.
  28. J. Y. Fang, “Self-Assembled Lipid Tubules: Synthesis, Characterization, and Ordered Arrays”. Mater. Res. Soc. Symp. Proc. 2006, 922E-U05-02.
  29. Y. Zhao, N. Mahajan, R. Lu, J. Y. Fang, “Liquid-Crystal Imaging of Molecular-Tilt Organization in Self-Assembled Tubules of Chiral Phospholipids”. Proceedings of the National Academy of Sciences USA 2005, 102, 7438. (It is highlighted in This Week of Proc. Natl. Acad. Sci. USA).
  30. C. Whitehouse, J. Y. Fang, A. Aggeli, M. Bell, R. M. Brydson, C. W. G. Fishwick, C. M. Knobler, J. Henderson, R. W. Owens, N. H., Thomson, N. Boden, “Adsorption and Self-assembly of Peptides on Substrates”. Angewandte Chemie International Edition 2005, 44, 1965. (It is listed as VIP paper and highlighted in Chemie ED News-Press Release).
  31. N. Mahajan, J. Y. Fang, “Two-Dimensional Ordered Arrays of Aligned Lipid Tubules on Substrates with Microfluidic Networks”. Langmuir 2005, 21, 3153. (It is featured on the cover of Langmuir and is highlighted on News Section of Analytical Chemistry).
  32. Y. H. Lin, H. W. Ren, Y. H. Wu, Y. Zhou, Y. Zhao, S. Gauza, J. Y. Fang, S. T. Wu, “Polarization-independent Liquid Crystal Phase Modulators using a Thin Polymer-Separated Double-Layered Structure.” Optics Express 2005, 13, 8746.
  33. N. Mahajan, R. Lu, S. T. Wu, J. Y. Fang, “Patterning Polymerized Lipid Vesicles with Soft Lithography”. Langmuir 2005, 21, 3132.
  34. I. Stanish, D. A. Lowy, Y. W. Lee, J. Y. Fang, E. Wong, R. Ray, A. Singh, “Structural and Electrochemical Characterization of Immobilized Polymerized Electroactive Lipid Vesicles”. Journal of Physical Chemistry B 2004, 108, 127.
  35. J. Y. Fang, “Viral Nanoparticles: Adsorption and Self-Organization on Surfaces”. Ency of Nanoscience & Nanotechnology 2004, 5, 3953. Invited Review Article.
  36. J. Y. Fang, W. Ma, J. Selinger, R. Shashidhar, “Imaging Biological Cells Using Liquid Crystals”. Langmuir 2003, 19, 2865. (It is featured on the cover of Langmuir and highlighted in Research News of Nature Materials 2004 and News of Biophotonics International Magazine 2004).
  37. C. D. Geddes, Gao, H.; Gryczynski, I.; Cryczynski, J. Y. Fang, J. R. Lakowicz, “Metal-Enhanced Fluorescence due to Silver Colloids on a Planar Surface: Potential Applications of Indocyanine Green to in Vivo Imaging”. Journal of Physical Chemistry A 2003, 107, 3443.
  38. C. D. Geddes, A. Parfenov, D. Roll, J. Y. Fang, J. R. Lakowicz, “Electrochemical and Laser Deposition of Silver Particles for Use in Metal-Enhanced Fluorescence”. Langmuir 2003, 19, 6236.
  39. B. R. Ratna, C. M. Soto, L. Danner, A. S. Blum, J. Y. Fang, Lin, J. E. Johnson. “Complex Pattern Formation by Cowpea Mosaic Virus Nanoparticles.” Langmuir 2003, 19, 489.
  40. J. Melicka, I. Gryczynsji, B. Maliwal, J. Y. Fang, J. R. Lakowicz, “Fluorescence Spectral Properties of Cyanine Dye-Labeled DNA-Near Silver Particles”. Biopolymer 2003, 72, 96.
  41. J. Melicka, I. Gryczynsji, J. Y. Fang, J. R. Lakowicz, “Fluorescence Spectral Properties of Cyanine Dye-Labeled DNA-Oligomers on Surfaces Coated with Silver Particles”. Analytical Biochemistry 2003, 317, 136.
  42. J. Melicka, I. Gryczynsji, J. Y. Fang, J. R. Lakowicz, “Increased Resonance Energy Transfer between Fluorophores Bound to DNA in Proximity to Metallic Silver Particles”. Analytical Biochemistry 2003, 315, 160.
  43. J. R. Lakowicz, Y. B. Shen, S. A’Auria, J. Malicka, J. Y. Fang, I. Gryczynsji. “Effects of Silver Island Films on Fluorescence Intensity, Lifetimes and Resonance Energy Transfer”. Analytical Biochemistry 2002, 301, 261.
  44. J. Melicka, I. Gryczynsji, J. Y. Fang, J. R. Lakowicz, “Photostability of Cy3-Labeled DNA in the Presence of Silver Particles”. Journal of Fluorescence 2002, 12, 439.
  45. J. Y. Fang, C. Soto, T. Lin, J. Johnson, B. R. Ratna, “Complex Pattern Formation by Cowpea Mosaic Virus Nanoparticles”. Langmuir 2002, 18, 308.
  46. J. Y. Fang, M. S. Chen, R. Shashidhar, “Photodimerization-Induced Positional Order in Self-Assembled Monolayers of Alkylsilanes”. Langmuir 2001, 17, 1549.
  47. J. Y. Fang, G. Whitaker, M. S. Chen, J. Naciri, R. Shashidhar, “Synthesis and Photodimerization of Self-Assembled Monolayers of 7-(8-Trimethoxysilane) Octenyloxy Coumarin”. Journal of Materials Chemistry 2001, 12, 2992.
  48. J. Naciri, J. Y. Fang, D. Shenoy, C. Dulcey, R. Shashidhar, “Photosensitive Triethoxysilane Derivatives for Alignment of Liquid Crystals”. Chemistry of Materials 2000, 12, 3288.
  49. P. A. Heiney, K. Grueneberg, J. Y. Fang, “Growth and Structure of Chromophores Functionalized Aminosilane Self-Assembled Monolayers”. Langmuir 2000, 16, 2651.
  50. J. Y. Fang, U. Gehlert, R. Shashidhar, C. M. Knobler, “Imaging the Azimuthal Tilt Order in Monolayers by liquid crystal Optical Amplification”. Langmuir 1999, 15, 297. (It is featured on the cover of Langmuir ).
  51. A. Buzin, Y. K. Godovsky, N. N. Makarova, J. Y. Fang, X. Wang, C. M. Knobler, “Stepwise Collapse of Monolayers of Cyclolinear Polysilaxanes at the Air-Water Interface”. Journal of Physical Chemistry B 1999, 103, 11372.
  52. U. Gehlert, J. Y. Fang, C. M. Knobler, “Relating the Organization of the Molecular Tilt Azimuth to Frictional Force Images in Lipid Monolayers Transferred to Solid Substrates”. Journal of Physical Chemistry B 1998, 102, 2614.
  53. Y. K. Godovsky, J. Y. Fang, C. M. Knobler, N. N. Makarova, Self-organized collapse of Langmuir monolayers of mesophase cyclolinear polyorganosiloxanes. Polymer Preprint 1998, 391, 543.
  54. R. A. Uphaus, J. Y. Fang, R. Picorel, G. Chumanov, J. Y. Wang, T. M. Cotton, M. Seibert, “X-ray Diffraction Studies of Isolated Photosystem II Reaction Centers in Monolayers and Multilayers”. Photochemistry and Photobiology 1997, 65, 673.
  55. J. Y. Fang, E. Teer, C. M. Knobler, “Boojums and the Shapes of Domains in Monolayer Films”. Physical Review E 1997, 56, 1859.
  56. J. Y. Fang, C. M. Knobler, H. Yokoyama, “Layer Growth in Collapsed Liquid Crystal Monolayers Studied by Scanning Force Microscopy”. Physics A 1997, 244, 91.
  57. J. Y. Fang, C. M. Knobler, M. Gingery, F. A. Eiserling, “Imaging Bacteriophage T4 Adsorbed on Patterned Self-Assembled Monolayers of Organosilanes by Scanning Force Microscopy”. Journal of Physical Chemistry B 1997, 101, 8692.
  58. J. Y. Fang, M. Dennin, C. M. Knobler, Y. K. Godovsky, N. N. Makarova, H. Yokoyama, “Structures of Collapsed Polysilaxane Monolayers Investigated by Scanning Force Microscopy”. Journal of Physical Chemistry B 1997, 101, 3147.
  59. J. Y. Fang, C. M. Knobler, “Phase-Separated Two-Component Self-Assembled Organosilane Monolayers and Their Use in Selective Adsorption of Proteins”. Langmuir 1996, 12, 1368.
  60. J. Y. Fang, C. M. Knobler, “Control of Density of Organosilane Monolayers by Langmuir-Blodgett Deposition”. Journal of Physical Chemistry 1995, 99, 10426.
  61. J. Y. Fang, D. Gaul, G. Chumanov, R. A. Uphaus, “Characterization of Photosynthetic Reaction Centers at the Air-Water Interface and in Langmuir-Blodgett Films”. Langmuir 1995, 11, 4366.
  62. J. Y. Fang, R. A. Uphaus, “Surface Pressure-Induced Layer Growth of a Langmuir Monolayer”. Langmuir 1994, 10, 1005.
  63. J. Y. Fang, R. A. Uphaus, P. Stroeve, “Imaging of Structured and Disordered Hemicyanine Dye Monolayers by Atomic Force Microscopy”. Thin Solid Films 1994, 243, 450.
  64. H. Lu, J. Y. Fang, N. Gu, Y. Wei, P. Stroeve, “Langmuir Monolayers Compressed by Laminar Flowing Subphase”. Journal of Colloid Interface Science 1993, 56, 462.
  65. J. Y. Fang, Z. H. Lu, Y. Wei, “Alignment Mechanism of Polyimide Langmuir-Blodget Films on Liquid Crystals”. Molecular Crystals and Liquid Crystals 1993, 225, 107.
  66. J. Y. Fang, Z. H. Lu, Y. Wei, P. Stroeve, “Alignment of Nematic Liquid Crystals by Pyrolyzed Polyimide Films”. Molecular Crystals and Liquid Crystals 1993, 226, 1.
  67. J. Y. Fang, Z. H. Lu, Y. Wei, “Study of Alignment Mechanism of Liquid Crystals on Oriented Polyimide Langmuir-Blodgett Films by STM”. Liquid Crystals 1993, 14, 1621.
  68. J. Y. Fang, Z. H. Lu, Y. Wei, P. Stroeve, “Anchoring Structure of Liquid Crystals on Polyimide Langmuir-Blodgett Films Observed by STM”. Physical Review A 1992, 46, 4963
  69. J. Y. Fang, Y. Wei, P. Stroeve, “Investigation of Alignment Properties of Lipid Monolayers on Liquid Crystals with STM”. Physics Letters A 1992, 66, 373.
  70. J. Y. Fang, Y. Wei, Z. M. Sun, “Influence of Phase Transition of Lipid Monolayers on Liquid Crystal Alignment”. Molecular Crystals and Liquid Crystals 1992, 222, 71.
  71. J. Y. Fang, Y. Wei, Z. M. Sun, “Aggregation of Cyanobiphenyl Liquid Crystals in Langmuir-Blodgett Multilayers”. Molecular Crystals and Liquid Crystals 1992, 210, 179.
  72. Z. H. Lu, J. Y. Fang, L. Wang, S. J. Xiao, Y. Wei, “Conductive Films Prepared by Pyrolysis of Photosensitive Polyimide Langmuir-Blodgett Films”. Solid State Communications 1992, 82, 711.
  73. J. Y. Fang, Z. H. Lu, S. P. Pan, Y. Wei, “Preparation and Characterization of Langmuir-Blodgett Films from New Crown Ethers”. Solid State Communications 1992, 83, 1023.
  74. Y. Wei, J. Y. Fang, “Alignment Properties of Langmuir-Blodgett Films on Liquid Crystals” in Nanostructures Based on Molecular Materials edited by W. Göpel and Ch. Ziegler. VCH, New York, 1992, P227-243.
  75. J. Y. Fang, N. B. Min, X. W. Tang, “ Brownian Motion of Particles with Short Time Intervals in Liquid Crystalline phase and Cell Cytoplasm”. Progress in Natural Science 1992, 2, 63.
  76. J. Y. Fang, Y. Wei, “Fabrication of Liquid Crystalline Films by Langmuir-Blodgett Deposition”. Chinese Physics Letters 1991, 8, 360. 4. J. Y. Fang, Z. M. Sun, Z. H. Lu, Y. Wei, P. Stroeve, “Langmuir-Blodgett Films of Hemicyanine Dye and Cadmium Stearate”. Chinese Physics Letters 1991, 8, 603.
  77. J. Y. Fang, S. J. Xiao, Y. Wei, P. Stroeve, “Structure and Optical Properties of Langmuir-Blodgett Films with Alternating Bilayers of Hemicyanine Dye and Stearial Acid”. Solid State Communications 1991, 79, 985.
  78. J. Y. Fang, Y. Wei, P. Stroeve, “Alignment of Liquid Crystalline Compounds on Hemicyanine Dye Langmuir-Blodgett Monolayers”. Physics Letters A 1991, 154, 396.
  79. Z. M. Sun, J. Y. Fang, N. B. Min, X. W. Tang, “Brownian Motion of Suspended Particles in Nematic Phases” Physics Letters A 1990, 145, 284.